macQsimal contributes to the strategic objectives of the Quantum Technologies Flagship in the sub-domain of Sensing and Metrology. The choice of atomic vapor cells makes coherent quantum processes available to applications: advanced cell-based sensors optimally exploit single-particle coherence, with the potential to harness also multi-particle quantum coherence for even greater sensitivity. Fabricating such atomic vapor cells as MEMS will allow for high-volume, high-reliability and low-cost deployment of miniaturised, integrated sensors, critical to wide-spread adoption. Through its balanced basic and applied research concept, macQsimal will also address the fundamental questions of quantum-enhancement techniques such as squeezing, entanglement and quantum non-demolition measures to form a basis for scientific breakthroughs of future research.